hrp0095p1-448 | Diabetes and Insulin | ESPE2022

The effect of physical activity on leptin and adiponectin in youth with T1D

Kaza Maria , Tsentidis Charalambos , Vlachopadopoulou Elpis , Sakou Ikboule , Paltoglou George , Mastorakos George , Karavanaki Kyriaki

Introduction: Exercise has pleiotropic positive effects for children and adolescents with Type 1 Diabetes (T1D). It improves glycemic control, daily insulin requirements, quality-of-life, morbidity and mortality rate. Leptin and adiponectin are adipocytokines produced by adipose tissue cells. Adiponectin is anti-atherogenic, anti-diabetic and anti-inflammatory, whereas leptin induces insulin resistance, has thermoregulatory properties and is pro-inflammatory.<...